Drug – bio-affecting and body treating compositions – Dentifrices – Phosphate compound containing
Patent
1992-08-26
1995-10-24
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Dentifrices
Phosphate compound containing
424 43, 424 45, 424602, 426 3, 423305, 423309, A61K 716, A61K 912, C01B 1516, C01B 2526
Patent
active
054608031
ABSTRACT:
This invention involves new compositions and methods of use and delivery of amorphous calcium compounds such as: amorphous calcium phosphate (ACP), amorphous calcium phosphate fluoride (ACPF), amorphous calcium carbonate phosphate (ACCP), amorphous calcium carbonate phosphate fluoride (ACCPF), and amorphous calcium fluoride (ACF) for use in remineralizing and fluoridating teeth. These amorphous compounds or solutions which form the amorphous compounds, when applied either onto or into dental tissue prevent and/or repair dental weaknesses such as dental caries, exposed roots and dentin sensitivity. The compounds have the highest solubilities, fastest formation rates and fastest conversion rates (to apatite) among all the calcium phosphates under physiological conditions. Moreover, in the presence to fluoride the amorphous compound convert rapidly to fluoride containing apatite.
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American Dental Association - Health Foundation
Griffin Ronald W.
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