Methods and compositions for mineralizing and flouridating calci

Details Methods and compositions for mineralizing and flouridating calci Methods and compositions for mineralizing and flouridating calci

1995-06-05

1996-10-08

Kight, John

Drug, bio-affecting and body treating compositions

Dentifrices

Phosphate compound containing

424 43, 424 44, 424 49, 424602, 106 35, 433215, 433226, 4332281, 433229, A61K 716, C09K 300, A01N 2502, A61C 500

Patent

active

055628958

ABSTRACT:
The invention involves new compositions and methods of use and delivery of amorphous calcium compounds such as: amorphous calcium phosphate (ACP), amorphous calcium phoshate fluoride (ACPF), amorphous calcium carbonate phosphate (ACCP), amorphous calcium carbonate phosphate fluoride (ACCPF), and amorphous calcium fluoride (ACF) for use in remineralizing and fluoridating teeth. These amorphous compounds or solutions which form the amorphous compounds, when applied either onto or into dental tissue prevent and/or repair dental weaknesses such as dental caries, exposed roots and dentin sensitivity. The compounds have the highest solubilities, fastest formation rates and fastest conversion rates (to apatite) among all the calcium phosphates under physiological conditions. Moreover, in the presence to fluoride the amorphous compound convert rapidly to fluoride containing apatite.

REFERENCES:
patent: 4219333 (1980-08-01), Harris
patent: 5037639 (1991-08-01), Tung
patent: 5268167 (1993-12-01), Tung
patent: 5427768 (1995-06-01), Tung
patent: 5437857 (1995-08-01), Tung
patent: 5460803 (1995-10-01), Tung

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