Methods and compositions for inhibition of BCL6 repression

Details Methods and compositions for inhibition of BCL6 repression Methods and compositions for inhibition of BCL6 repression

2011-04-05

2011-04-05

Audet, Maury (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

C514S001100, C424S001690

Reexamination Certificate

active

07919578

ABSTRACT:
Provided are peptides or mimetics that block corepressor binding to a BCL6 lateral groove. Also provided are methods of blocking corepressor binding to the BCL6 lateral groove. Additionally, methods of inhibiting BCL6 repression in a mammalian, cell, and methods of treating a mammal with cancer are provided.

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