Methods and compositions for inhibiting tumor growth

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

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Details

C552S510000

Reexamination Certificate

active

07851462

ABSTRACT:
The present invention relates to novel betulinic acid derivatives with increased activity for the treatment of carcinomas and HIV diseases, a method for preparing such novel betulinic acid derivatives as well as their use as pharmaceuticals.

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Greene and Wuts, “Chapter 2: Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols,” In: Protective Groups in Organic Synthesis3rdEd., John Wiley&Sons, Inc., pp. 17-245, 1999.
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Willmann et al., “Characterization of NVX-207, a novel betulinic acid-derived anti-cancer compound,”European Journal of Clinical Investigation, 39:384-94, 2009.

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