Methods and compositions for inhibiting the growth of neoplastic

Details Methods and compositions for inhibiting the growth of neoplastic Methods and compositions for inhibiting the growth of neoplastic

1988-02-16

1991-06-25

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

514307, 514 2, 424 855, 424 856, 424 857, A61K 31485, A61K 3766

Patent

active

050265440

ABSTRACT:
The present disclosure is directed to the use of combinations of a papaverine family member agent together with an interferon for the treatment of proliferative disorders such as neoplasias and hyperplasias. Disclosed are compositions and formulations which take advantage of the synergistic antiproliferative activities of these agents and the use of these compositions and formulations in the treatment of these disorders.

REFERENCES:
patent: 4018927 (1977-04-01), Voorhees
patent: 4800081 (1989-01-01), Albrecht et al.
Interferon: An Anti-Cancer Agent? Priestman, Cancer Treatment Reviews (1979), 6,223-237.
Does Interferon Cure Cancer? Sikora, British Medical Journal 281,855 (1980).
Coburn et al. (1979), Neoplastic Transformation in Differentiated Epithelial Cell Systems., In Vitro, eds. Franks & Wigley, Acad. Press, N.Y., pp. 113-114.

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