Methods and compositions for immunologically modulating growth h

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...

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530402, 530810, 424 88, 430519, 430543, C12P 2100, C12P 1934, C12N 1500, C07H 1512

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048576379

ABSTRACT:
The activity of growth-associated receptors is modulated in vivo in a controlled and reproducible fashion by immunizing animals against target growth-associated receptors. This is accomplished by the use of immunogens predetermined to induce primarily agonist or antagonist responses. The immunogens include anti-ligand antibodies and receptor derivatives.

REFERENCES:
patent: 4761371 (1988-08-01), Bell et al.
Heinemann et al. "Modulation of acetylcholine receptor by antibody against the receptor", Proc. Natl. Acad. Sci. USA, vol. 74, No. 7, 3090-3094, Jul. 1977.
Couraud et al., "Antibodies Raised Against .beta.-Adrenergic Receptors Stimulate Adenylate Cyclase", Biochem Biophys Res Comm., vol. 99, No. 4, 1295-1302, Apr. 1981.
Farid, Nadir R. "Immunology Letters", 9:191-199, (Apr. 1985).
Kelsoe, G. et al., "Immunological Review", 52:75-88, (1980).
Noseworthy, J. N. et al., "J. of Immunology", 131(5):2533-2538, (Nov. 1983).
Flier, J. S. et al., "Science", 190:63-65, (Oct. 1975).
Kennedy, R. C. et al., "Science", 22:853-855, (Aug. 1983).
Marx, J. L., "Science", 228:162-165, (Apr. 1985).
Venter, J. C. et al., "Federation Proceedings", 43(10):2532-2539, (Jul. 1984).
Couraud, P. O. et al., "J. Exp. Med.", 157:1369-1378, (May 1983).
McNamara, M. K. et al., "Science", 226:1325-1326, (Dec. 1984).
Sacks, D. L. et al., "J. Exp. Med.", 155:1108-1119, (Apr. 1982).
Schreiber, A. B. et al., "Proc. Natl. Acad. Sci. USA", 77(12):7385-7389, (Dec. 1980).
Ng, D. S. et al., "European J. Pharmacology", 102:187-190 (1984).
Ibbotson, K. J. et al., "Endocrinology", 116(1):469-471, (1985), (Given to Postal Service on Dec. 20, 1984).
Djiane, J. et al., "Proc. Natl. Acad. Sci. USA", 78(12):7445-7448, (Dec. 1981).
Cadman, H. F. et al., "FEBS Letters", 137(1):149-152, (Jan. 1982).
Leiber et al., "Proc. Natl. Acad. Sci. USA", 81:4331-4334, (Jul. 1984).
Jacobs, S. et al., "Science", 200:1282-1283, (Jun. 1978).
Fernandez-Pol, J. A. et al., "J. Biol. Chem.", 260(8):5003-5011, (Apr. 1985).
Kahn, C. R. et al., "J. Clin. Invest.", 60:1094-1106, (Nov. 1977).
Surowy, T. K. et al., "Mol. Immunol.", 21(5):345-352, (1984).
Barnard, R. "Biochem. J.", 231:459-468, (1985).
Duplock, R. C. et al., Abstract from Mtg. of The Endocrine Society of Australia, Adelade, 1985.
Valente, W. A. et al., "New Eng. J. Med.", 309(17):1028-1034, (Oct. 1983).
Valente, W. A. et al., "Proc. Natl. Acad. Sci. USA", 79:6680-6684, (Nov. 1982).
Kris et al., Cell 40:619-625, (1985).

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