Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-10-17
2006-10-17
Andres, Janet L. (Department: 1646)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C435S252300, C435S254110
Reexamination Certificate
active
07122305
ABSTRACT:
The present invention makes available a rapid, effective assay for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a cellular receptor or ion channel. The subject assay enables rapid screening of large numbers of polypeptides in a library to identifying those polypeptides which induce or antagonize receptor bioactivity. The subject assay is particularly amenable for identifying surrogate ligands for orphan receptors.
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Broach James
Fowlkes Dana M.
Klein Christine A.
Manfredi John
Murphy Andrew J.
Andres Janet L.
Cadus Technologies, Inc.
Chandra Gyan
Edwards Angell Palmer & & Dodge LLP
Lauro, Esq. Peter C.
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