Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-05
1997-08-19
Eisenschenk, Frank C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
5303871, 5303873, 536 2353, C12N 512, C12N 1513, C07K 1900, C07H 2104
Patent
active
056587635
ABSTRACT:
Disclosed herein are improved methods and compositions for achieving enhanced protein production expressed from non-native gene constructs, including single chain sFv and derivative sequences. The methods and compositions are particularly useful for creating stably transfected, contitutively expressing immortalized mammalian cell lines that exhibit high recombinant protein productivity while maintaining a low copy number per cell of the non-native recombinant DNA sequence encoding the protein of interest.
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Dorai Haimanti
Oppermann Hermann
Creative BioMolecules, Inc.
Eisenschenk Frank C.
LandOfFree
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