Methods and compositions for genetically detecting improved...

Details Methods and compositions for genetically detecting improved... Methods and compositions for genetically detecting improved...

2011-02-15

2011-02-15

Kapushoc, Stephen (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C536S023100

Reexamination Certificate

active

07888021

ABSTRACT:
An isolated nucleic acid molecule comprising a polymorphic site selected from the group consisting of positions 164, 269, 284, 407 and 989 of SEQ ID NO: 1, an array or a kit comprising the same. Also provided are a method for detecting single nucleotide polymorphism (SNP) in bovine proteinase inhibitor (PI) gene, a method for haplotyping a bovine cell, a method for progeny testing of cattle based on said haplotyping, a method for selectively breeding of cattle based on haplotyping a parent animal. The present invention further provides a method for testing a dairy cattle for its milk production trait, comprising haplotyping its cells, wherein a cattle having haplotypes 1, 3, 4 or 5 indicates that the cattle has desirable milk production trait. Haplotype 1 indicates that the cattle has the most desirable milk production trait.

REFERENCES:
Lohuis M.M. Theriogeneology (1995) 43:51-60.
Thisted R.A. “What is a P-value?” (May 25, 1998) from http://www.stat.uchicago.edu/˜thisted, pp. 1-6.
Hacker U.T. et al. Gut (1997) vol. 40, No. 5, pp. 623-627.

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