Methods and compositions for expressing polynucleotides...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S325000, C435S320100, C435S069100, C800S013000

Reexamination Certificate

active

06914136

ABSTRACT:
The present invention generally relates to promoters, enhancers and other regulatory elements of smooth muscle cells (“SMC”). The invention more particularly relates to methods for the targeted knockout, or over-expression, of genes of interest within smooth muscle cells or within a subtype of smooth muscle cells. The invention further relates to methods of conferring polynucleotide expression in vivo specifically in smooth muscle cells or in subtypes of smooth muscle cells.

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