Methods and compositions for efficient gene transfer using...

Details Methods and compositions for efficient gene transfer using... Methods and compositions for efficient gene transfer using...

2006-10-24

2006-10-24

Guzo, David (Department: 1636)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C424S093100, C424S093600, C435S320100, C435S455000, C435S457000

Reexamination Certificate

active

07125549

ABSTRACT:
The invention includes a viral vector method and composition comprising transcomplementary replication incompetent viral vectors, preferably adenoviral vectors, which are cotransformed to a recipient cell. The two vectors complement each other and thus allow viral replication, in a synergistic combination which enhances both gene delivery and gene expression of genetic sequences contained within the vector.

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