Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens
Reexamination Certificate
2007-12-04
2007-12-04
Le, Long V. (Department: 1641)
Chemistry: analytical and immunological testing
Involving producing or treating antigen or hapten
Producing labeled antigens
C436S172000, C436S800000, C435S968000, C424S178100
Reexamination Certificate
active
10776840
ABSTRACT:
The present invention discloses dye-azide derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds of the present invention may contain either a mixture of Type 1 and Type 2 agents or a single entity that integrates both units in the same molecules. The compounds are designed to produce both Type 1 and Type 2 phototherapeutic effect at once using dual wavelength light source that will produce singlet oxygen and nitrene at the lesion of interest.
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Achilefu Samuel I.
Bugaj Joseph E.
Dorshow Richard B.
Rajagopalan Raghavan
Haq Shafiqul
Le Long V.
Mallinckrodt Inc
Thompson Hine LLP
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