Methods and compositions for dual phototherapy

Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens

Reexamination Certificate

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C436S172000, C436S800000, C435S968000, C424S178100

Reexamination Certificate

active

10776840

ABSTRACT:
The present invention discloses dye-azide derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds of the present invention may contain either a mixture of Type 1 and Type 2 agents or a single entity that integrates both units in the same molecules. The compounds are designed to produce both Type 1 and Type 2 phototherapeutic effect at once using dual wavelength light source that will produce singlet oxygen and nitrene at the lesion of interest.

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