Methods and compositions for diagnostic and therapeutic...

Details Methods and compositions for diagnostic and therapeutic... Methods and compositions for diagnostic and therapeutic...

2007-06-19

2010-06-15

Saeed, Kamal A (Department: 1626)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Diagnostic or test agent produces in vivo fluorescence

C514S279000, C546S037000

Reexamination Certificate

active

07736624

ABSTRACT:
The presently disclosed subject matter provides compositions that selectively bind cyclooxygenase-2 and comprise a therapeutic and/or diagnostic moiety. Also provided are methods for using the disclosed compositions for diagnosing (i.e., by imaging) a target cell and/or treating a disorder associated with a cyclooxygenase-2 biological activity.

REFERENCES:
patent: 3161654 (1964-12-01), Shen
patent: 3196162 (1965-07-01), Lewis et al.
patent: 3285908 (1966-11-01), Shen
patent: 3336194 (1967-08-01), Shen
patent: 3470203 (1969-09-01), Gal et al.
patent: 3654349 (1972-04-01), Shen et al.
patent: 3725548 (1973-04-01), Shen et al.
patent: 4229447 (1980-10-01), Porter
patent: 4412994 (1983-11-01), Sloan et al.
patent: 4851426 (1989-07-01), Ladkani et al.
patent: 5016652 (1991-05-01), Rose et al.
patent: 5032588 (1991-07-01), Brooks et al.
patent: 5093356 (1992-03-01), Yves et al.
patent: 5360925 (1994-11-01), Chabrier de Lassauniere et al.
patent: 5436265 (1995-07-01), Black et al.
patent: 5504086 (1996-04-01), Ellinwood, Jr. et al.
patent: 5510368 (1996-04-01), Lau et al.
patent: 5607966 (1997-03-01), Hellberg et al.
patent: 5681964 (1997-10-01), Ashton et al.
patent: 5811425 (1998-09-01), Woods et al.
patent: 5811438 (1998-09-01), Hellberg et al.
patent: 5861419 (1999-01-01), Dube et al.
patent: 5922742 (1999-07-01), Black et al.
patent: 5965619 (1999-10-01), Rifat et al.
patent: 6045773 (2000-04-01), Isakson et al.
patent: 6048850 (2000-04-01), Young et al.
patent: 6207700 (2001-03-01), Kalgutkar et al.
patent: 6277878 (2001-08-01), Nakao et al.
patent: 6306890 (2001-10-01), Kalgutkar et al.
patent: 6399647 (2002-06-01), Kalgutkar et al.
patent: 6762182 (2004-07-01), Kalgutkar et al.
patent: 6933316 (2005-08-01), Hsieh et al.
patent: 7491744 (2009-02-01), Marnett et al.
patent: 2001/0034361 (2001-10-01), Kalgutkar et al.
patent: 2003/1954244 (2003-10-01), Hsieh et al.
patent: 2005/0002859 (2005-01-01), Marnett et al.
patent: 2005/0250839 (2005-11-01), Marnett et al.
patent: 2009/0118290 (2009-05-01), Marnett et al.
patent: 1337851 (2002-02-01), None
patent: 2735537 (1979-02-01), None
patent: 2926472 (1981-01-01), None
patent: 3145465 (1983-05-01), None
patent: 3235850 (1983-08-01), None
patent: 3206885 (1983-09-01), None
patent: 10163426 (2003-07-01), None
patent: 0051278 (1982-05-01), None
patent: 0080271 (1983-06-01), None
patent: 0144845 (1985-06-01), None
patent: 0327766 (1989-08-01), None
patent: 335164 (1989-10-01), None
patent: 335545 (1989-10-01), None
patent: 342682 (1989-11-01), None
patent: 1148783 (2006-06-01), None
patent: 432545 (1976-11-01), None
patent: 2392008 (1978-12-01), None
patent: 54090174 (1979-07-01), None
patent: 58201763 (1983-11-01), None
patent: 59161358 (1984-09-01), None
patent: 60152462 (1985-08-01), None
patent: 61060649 (1986-03-01), None
patent: 63196598 (1988-08-01), None
patent: 63275593 (1988-11-01), None
patent: 8105139 (1982-06-01), None
patent: WO95/004030 (1995-02-01), None
patent: WO95/020567 (1995-08-01), None
patent: WO00/040087 (2000-07-01), None
patent: WO00/040088 (2000-07-01), None
patent: WO01/015686 (2001-03-01), None
patent: WO02/008188 (2002-01-01), None
patent: WO02/020478 (2002-03-01), None
patent: WO02/060438 (2002-08-01), None
patent: WO02/028831 (2002-11-01), None
patent: WO2004/020409 (2004-03-01), None
patent: WO2005/002293 (2005-01-01), None
patent: WO2005/112921 (2005-12-01), None
Timofeevski et al., Isoform-Selective Interaction of Cyclooxygenase-2 with Indomethacin Amides Studied by Real-Time Fluorescence, Inhibition Kinetics, and Site-Directed Mutagenesis, 2002, Biochemistry, 41, p. 9655.
Besselievre et al.,Structural Immunochemistry of Melatonin-BSA Binding, Model of Amino and Indole Groups Cross-Linking. Biomedicine Express. vol. 33, No. 7 pp. 226-228 (1980).
Correspondence from foreign patent attorney regarding Chinese Patent Application No. 99816425.9 dated Jun. 21, 2004.
Correspondence from foreign patent attorney regarding Israel Patent Application No. 144,127 dated May 26, 2005.
Correspondence from foreign patent attorney regarding Israel Patent Application No. 144,127 dated Dec. 11, 2005.
Correspondence from foreign patent attorney regarding Notice of Allowance corresponding to Israel Patent Application No. 144,127 dated Jul. 5, 2006.
Decision to grant a European patent pursuant to article 97(2) EPC corresponding to European Patent Application No. 00957717.2-2117 dated Sep. 20, 2007.
Decision to grant a European patent pursuant to article 97(2) EPC corresponding to European Patent Application No. 99967416.1-2107 dated May 11, 2006.
Decision to grant a European patent pursuant to article 97(2) EPC corresponding to European Patent Application No. 99967417.9-1521 dated Apr. 26, 2007.
Del Rosario et al.,Synthesis of[C-11]indomethacin methyl ester for in vivo brain studies of cyclooxygenase 2. Journal of Nuclear Medicine. vol. 37, No. 5 (1996) [Abstract].
European Search Report corresponding to European Patent Application No. 00957717.2-2123 dated Nov. 16, 2004.
European Search Report corresponding to European Patent Application No. 99967416.1-2107 dated Apr. 8, 2003.
Faust et al.,Mapping the Melatonin Receptor. 6. Melatonin Agonists and Antagonists Derived from 6H-Isoindolo[2,1-a]indoles, 5,6-Dihydroindolo[2,1-a]isoquinolines, and 6,7-Dihydro-5H-benzo[ c]azepino[2,1-a]indoles. Journal of Medicinal Chemistry. vol. 43 pp. 1050-1061 (2000).
Flaugh et al.,Synthesis and Evaluation of the Antiovulatory Activity of a Variety of Melatonin Analogues. Journal of Medicinal Chemistry. vol. 22, No. 1 pp. 63-69 (1979).
Frohn et al., Structure —Activity Relationship of Melatonin Analogues.Life Sciences. vol. 27, No. 22 pp. 2043-2046 (1980).
Issued Patent corresponding to Chinese Patent No. ZL 99816425.9 dated Apr. 6, 2005.
Issued Patent corresponding to Israel Patent No. 144127 dated Nov. 3, 2007.
Issued Patent corresponding to Republic of China Invention Patent No. I286474 dated Sep. 11, 2007.
Kalgutkar et al.,Ester and Amide Derivatives of the Nonsteroidal Antiinflammatory Drug, Cyclooxygenase-2 Inhibitors. Journal of Medicinal Chemistry. vol. 43, No. 15 pp. 2860-2870 (2000).
McMurray, R.W., and Hardy, K.J.,Cox-2 Inhibitors: Today and Tomorrow. The American Journal of the Medical Sciences. vol. 323, No. 4 pp. 181-189 (2002).
Mor et al.,Melatonin Receptor Ligands: Synthesis of New Melatonin Derivatives and Comprehensive Comparative Molecular Field Analysis(CoMFA)Study. Journal of Medicinal Chemistry. vol. 41, No. 20 pp. 3831-3844 (1998).
Notice of Acceptance corresponding to Australian Patent Application No. 23697/00 dated Mar. 19, 2004.
Notice of Acceptance corresponding to Australian Patent Application No. 23698/00 dated Apr. 1, 2003.
Notice of Acceptance corresponding to Australian Patent Application No. 69297/00 dated Mar. 9, 2004.
Notice of Allowance corresponding to U.S. Appl. No. 09/226,693 dated Oct. 24, 2000.
Notice of Allowance corresponding to U.S. Appl. No. 09/385,748 dated Jun. 5, 2001.
Notice of Allowance corresponding to U.S. Appl. No. 09/818,201 dated Jan. 15, 2002.
Notice of Allowance corresponding to U.S. Appl. No. 09/869,384 dated Nov. 6, 2003.
Notice of Decision of Granting Patent Right for Invention corresponding to Chinese Patent Application No. 99816425.9 dated Dec. 3, 2004.
Official Action corresponding to Australian Patent Application No. 23697/00 dated Nov. 15, 2002.
Official Action corresponding to Australian Patent Application No. 23697/00 dated Dec. 16, 2003.
Official Action corresponding to Australian Patent Application No. 23698/00 dated Nov. 15, 2002.
Official Action corresponding to Australian Patent Application No. 69297/00 dated Nov. 17, 2003.
Official Action corresponding to Chinese Patent Application No. 99816425.9 dated Aug. 20, 2003.
Official Action corresponding to European Patent Application No. 99 967 416.1-2107 dated May 27, 2004.
Official Action corresponding to European Patent Application No. 00957717.2-2117 dated Jul. 13, 2006.
Official Action corresponding to Republic of China (Taiwan) Patent Application No. 89117582 dated Dec. 20, 2003.
Official Action corresponding to Rep

Affiliated with

Also associated with

Rating

Methods and compositions for diagnostic and therapeutic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and compositions for diagnostic and therapeutic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for diagnostic and therapeutic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4165476