Methods and compositions for diagnosis and treatment of iron...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C424S001410, C424S001570, C424S001690, C424S130100, C424S139100, C424S143100, C424S156100, C424S184100, C424S193100, C424S278100, C424S529000, C435S325000, C435S344000, C436S063000, C436S066000, C530S388220

Reexamination Certificate

active

10956250

ABSTRACT:
Methods and compositions are provided for the diagnosis and treatment of iron misregulation diseases, including HFE polypeptides, agonists, and antagonists, and transferrin receptor agonists and antagonists.

REFERENCES:
patent: 4399216 (1983-08-01), Axel et al.
patent: 4434156 (1984-02-01), Trowbridge
patent: 4511503 (1985-04-01), Olson et al.
patent: 4666927 (1987-05-01), Hider et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4711845 (1987-12-01), Gelfand et al.
patent: 4912118 (1990-03-01), Hider et al.
patent: 5075469 (1991-12-01), Chevion
patent: 5104865 (1992-04-01), Hider et al.
patent: 5116964 (1992-05-01), Capon et al.
patent: 5185368 (1993-02-01), Peter et al.
patent: 5256676 (1993-10-01), Hider et al.
patent: 5328992 (1994-07-01), Peter et al.
patent: 5385918 (1995-01-01), Connell et al.
patent: 5399346 (1995-03-01), Anderson et al.
patent: 5420008 (1995-05-01), Nishida et al.
patent: 5424057 (1995-06-01), Peter et al.
patent: 5582979 (1996-12-01), Weber
patent: 5705343 (1998-01-01), Drayna et al.
patent: 5712098 (1998-01-01), Tsuchihashi et al.
patent: 5719125 (1998-02-01), Suzuki et al.
patent: 5753438 (1998-05-01), Drayna et al.
patent: 5872237 (1999-02-01), Feder et al.
patent: 6025130 (2000-02-01), Thomas et al.
patent: 6140305 (2000-10-01), Thomas et al.
patent: 6228594 (2001-05-01), Thomas et al.
patent: 6284732 (2001-09-01), Feder et al.
patent: 6391852 (2002-05-01), Feder et al.
patent: 2115221 (1994-08-01), None
patent: 2115222 (1994-08-01), None
patent: 2115224 (1994-08-01), None
patent: 208 609 (1984-04-01), None
patent: 4 327 226 (1995-02-01), None
patent: 0 315 434 (1989-05-01), None
patent: 0 346 281 (1989-12-01), None
patent: 97910741 (2003-06-01), None
patent: 2 293 269 (1996-03-01), None
patent: WO 94/01463 (1994-01-01), None
patent: WO 94/04186 (1994-03-01), None
patent: WO 94/11367 (1994-05-01), None
patent: WO 94/21243 (1994-09-01), None
patent: WO 95/16663 (1995-06-01), None
patent: WO 96/06583 (1996-03-01), None
patent: WO 96/17870 (1996-06-01), None
patent: WO 96/35802 (1996-11-01), None
patent: WO 97/38137 (1997-10-01), None
patent: WO 98/56814 (1998-12-01), None
Harrison et al. 2003. J. of Hepatology. vol. 38:S14-S23.
Hemochromatosis-Genetics Home Reference. http://ghr.nlm.nih.giv/condition+hemochromatosis□□.
Beutler, E. et al., “Mutation Analysis in Hereditary Hemochromatosis”Blood Cells, Molecules, and Diseases(1996), 22(16): 187-194.
Gasparini, et al, “Where does the gene for Hemochromatosis lie in relation to HLA-A”,Hepatology(1994), 19: 1050-1056.
VogeL, et al., “Human Chromosomes,” Springer-Verlag (1992) pp. 18-81.
Seese, et al., “Localization of the Hemochromatosis Disease Gene : Linkage Disequilibrium Analysis using an American Patient Collection,”Blood Cells, Molecules&Diseases(1996) 22:36-46.
Gandon et al., “Linkage Disequilibrium and Extended Haplotypes in the HLA-A to D6S105 Region: Implications for Mapping the Hemochromatosis Gene (HFE),”J. Hum. Genet.(1996) 97(1):103-13.
Adams, M.D., et al., “Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project,” Science (1991) 252:1651-1656 (National Institutes of Health).
Amadou, C., et al., “Localization of New Genes and Markers to the Distal Part of the Human Major Histocompatibility Complex(MHC)Region and Comparison With the Mouse: New Insights Into the Evolution of Mammalian Genomes,” Genomics (1995) 26:9-20.
Anderson, J.R., et al., “Precipitating Autoantibodies in Sjögren's Disease,” Lancet (1961) 2:456-460 (Glasgow Univ.).
Bacon, B.R., “Causes of Iron Overload,” N. Engl. J. Med. (1992) 326(2):126-127 (St. Louis Univ. School of Medicine).
Balan, V., et al., “Screening for Hemochromatosis: A Cost-Effectiveness Study Based on 12,258 Patients,” Gastroenterology (1994) 107:453-459.
Barton, J.C., et al., “Blood Lead Concentrations in Hereditary Hemochromatosis,” J. Lab. Clin. Med. (1994) 124(2):193-198.
Barton, J.C., et al., “Hemochromatosis: The Genetic Disorder of the Twenty-First Century,” Nature Medicine (1996) 2(4):394-395 (Brookwood Medical Center).
Beaucage, S.L., et al., “Deoxynucleoside Phosphoramidites-A New Class of Key Intermediates for Deoxypolynucleotide Synthesis,” Tetrahedron Letters (1981) 22(20):1859-1862.
Beggs, J.D., “Transformation of Yeast by a Replicating Hybrid Plasmid,” Nature (1978) 275:104-109.
Benton, W.D., et al., “Screening λgt Recombinant Clones by Hybridization to Single Plaques in situ,” Science (1977) 196:180-182 (National Institutes of Health).
Beutler, E., et al., “A Strategy for Cloning the Hereditary Hemochromatosis Gene,” Blood Cells, Molecules, and Diseases (1995) 21(21):207-216.
Boretto, J., et al., “Anonymous Markers Located on Chromosome 6 in the HLA-A Class I Region: Allelic Distribution in Genetic Haemochromatosis,” Hum. Genet. (1992) 89:33-36 (Institut National de la Santa et de la Recherche Medicale).
Botstein, D., et al., “Sterile Host Yeasts(SHY):A Eukaryotic System of Biological Containment for Recombinant DNA Experiments,” Gene (1979) 8:17-24 (American Cancer Society).
Broach, J.R., et al., “Transformation in Yeast: Development of a Hybrid Cloning Vector and Isolation of the CANI Gene,” Gene (1979) 8:121-133 (National Institutes of Health).
Calandro, L.M., et al., “Characterization of a Recombinant That Locates the Hereditary Hemochromatosis Gene Telomeric to HLA-F,” Hum. Genet. (1995) 96:339-342 (Kaiser Foundation Research Institute).
Camaschella, C., et al., “Hereditary Hemochromatosis: Recent Advances in Molecular Genetics and Clinical Management,” Haematologica (1997) 82:77-84 (BioMed).
Campbell, A.M., “Monoclonal Antibody Technology,” Elsevier Science Publishers (1985) Chapter 1 pp. 1-32 (ISBN 0-444-80592-3).
Capecchi, M.R., “Altering the Genome by Homologous Recombination,” Science (1989) 244:1288-1292 (Univ. of Utah Medical Center).
Cartwright, G.E., et al., “Inheritance of Hemochromatosis: Linkage to HLA,” Trans. Assoc. Am. Phys. (1978) 91:273-281 (National Institutes of Health).
Chen, X., et al., “Template-Directed Dye-Terminator Incorporation(TDI)Assay: A Homogeneous DNA Diagnostic Method Based on Fluorescence Resonance Energy Transfer,” Nucl. Acids Res. (1997) 25(2):347-353 (U.S. Dept. of Energy).
Chong, S.S., et al., “Molecular Cloning of the cDNA Encoding a Human Renal Sodium Phosphate Transport Protein and its Assignment to Chromosome 6p21.3-p23,” Genomics (1993) 18:355-359.
Church, D.M., et al., “Isolation of Genes From Complex Sources of Mammalian Genomic DNA Using Exon Amplificaiton,” Nature Genetics (1994) 6:98-105 (National Institutes of Health).
Clark, G., et al., “Characterization of a Soluble Cytoplasmic Antigen Reactive With Sera From Patients With Systemic Lupus Erythmatosus,” J. Immunol. (1969) 102(1):117-122 (Univ. of New York Dept. of Medicine).
Cornall, R.J., et al., “The Generation of a Library of PCR-Analyzed Microsatellite Variants for Genetic Mapping of the Mouse Genome,” Genomics (1991) 10:874-881.
Crawford, D.H.G., et al., “Evidence That the Ancestral Haplotype in Australian Hemochromatosis Patients May be Associated With a Common Mutation in the Gene,” Am. J. Hum. Genet. (1995) 57:362-367.
Crystal, R.G., “Gene Therapy Strategies for Pulmonary Disease,” Am. J. Med. (1992) 92(6A):6A-44S-6A-52S (National Institutes of Health).
Darnell, J., “Tools of Molecular Cell Biology: Molecular Technology,” Scientific American Books (1986) pp. 227-229 (Rockefeller Univ.).
Dausset, J., et al., “Centre d'Etude du Polymorphisme Humain(CEPH):Collaborative Genetic Mapping of the Human Genome,” Genomics (1990) 6:575-577.
de Sousa, M., et al., “Iron Overload in β2-Microglobulin-Deficient Mice,” Imm

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