Methods and compositions for determining the pathogenic...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

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C435S006120, C435S029000

Reexamination Certificate

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07919234

ABSTRACT:
Methods and compositions for the detection of disease caused by infectious agents and microbes are provided. In particular, methods and compositions comprising novel combinations of nucleic acid amplification and drug susceptibility technologies are provided. In certain embodiments, the present invention enables the detection of infectious agents and microbes as well as providing information concerning the viability status of the agent or microbe. In one embodiment, the present invention is used for the detection of mycobacterial infections, including, but not limited to, tuberculosis.

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patent: 2002/0156016 (2002-10-01), Minuk
Drug Resistance Threatens to Reverse Medical Progress, www.who.int—Press Release, pp. 1-4, Jun. 12, 2000.
PCT/US08/04491—International Search Report,PCT—International Search Report, pp. 1-8, Jun. 20, 2008.
Dye et al., Consensus Statement, Global Burden of Tuberculosis: Estimated Incidence, Prevalence, and Mortality by County. WHO Global Surveillance and Monitoring Project,Journal of the American Medical Association, vol./Iss: 282 (7), pp. 677-686, Aug. 18, 1999.
Lewis, R., The Rise of Antibiotic-Resistant Infections,online—www.fda.gov, pp. 1-7, Sep. 1, 1995.

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