Methods and compositions for detecting anti-hepatitis E virus ac

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 792, 436518, 436820, C12Q 170

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060226854

ABSTRACT:
The present invention provides antigenic peptides and polypeptides of hepatitis E virus. Also provided are mixtures of conjugated and unconjugated peptides of the present invention. Methods of detecting hepatitis E viral infection in a subject using the peptides and peptide mixtures of the present invention are also contemplated.

REFERENCES:
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Tam et al. Virology 185:120-131, Nov. 1991.
Yarborough et al. J. Virol. 65:5790-5796, Aug. 1991.
Ichikawa et al. Microbiol. Immunol. 35(7):535-543, Apr. 1991.
Reyes et al. Gastroenterologia Japonica 26(3):142-147, 1991.
Reyes et al. Elsevier Sci. Pub. B.V. (Biomed. Div.) Chapter 43:237-245, 1991.
Reyes et al. Science 245:1335-1339, Mar. 1990.
Bradley et al. Proc.Natl. Acad. Sci. USA 84:6277-2681, May 1987.
Favorov et al., Abstract #1662, Abstracts of the 1992 ICAAC , "Peptide EIA for detection of antibody to hepatitis E virus," p. 388.
Dawson et al., Journal of Virological Merthods 38:175-186 (1992).
Kaur et al., Proc. Natl. Acad. Sci. USA 89:3855-3858 (May, 1992).

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