Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2008-09-04
2011-11-29
Cordero Garcia, Marcela M (Department: 1654)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C514S001100, C514S007600, C514S021400
Reexamination Certificate
active
08067021
ABSTRACT:
The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions.
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Buehrer Benjamin Marcus
Chen Yuchen
Hamilton Paul
Juzumiene Dalia
Nair Shrikumar
Affinergy, Inc.
Cordero Garcia Marcela M
Kiefer Laura L.
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