Methods and compositions for combinatorial-based discovery of ne

Details Methods and compositions for combinatorial-based discovery of ne Methods and compositions for combinatorial-based discovery of ne

1996-07-09

1997-11-04

Ketter, James

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4352544, C12N 1504, C12N 512

Patent

active

056838999

ABSTRACT:
The present invention prowdes methods and compositions for producing and screening combinatorial libraries of multimeric proteins. The present invention relies on the use of filamentous fungal heterokaryons that are produced using two or more parent strains into which a population of DNA molecules encoding variants of a multimeric protein have been introduced.

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