Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing
Reexamination Certificate
2006-01-30
2010-10-19
Hill, Kevin K. (Department: 1633)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
C424S093600, C424S094500, C435S183000, C435S194000, C435S235100, C435S320100, C536S023100, C536S023400, C536S023700, C536S023720
Reexamination Certificate
active
07815902
ABSTRACT:
The invention comprises a novel virus that can kill mammalian cancer cells efficiently. The virus produces a novel protein that converts two non-toxic prodrugs into potent chemotherapeutic agents. These chemotherapeutic agents are produced locally and help the virus kill the cancer cells as well as sensitize them to radiation. In preclinical studies, the virus has proven effective at killing a variety of mammalian cancer cells either alone or when combined with prodrug therapy and/or radiation therapy. The invention may provide a safe and effective treatment for human cancer.
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patent: WO-01/04282 (2001-01-01), None
patent: WO-2005/007109 (2005-01-01), None
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Barton Ken
Freytag Svend O.
Kim Jae Ho
Paielli Dell
Henry Ford Health System
Hill Kevin K.
Kamp James F.
Rader & Fishman & Grauer, PLLC
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