Methods and compositions for ATP-sensitive K.sup.+ channel inhib

Details Methods and compositions for ATP-sensitive K.sup.+ channel inhib Methods and compositions for ATP-sensitive K.sup.+ channel inhib

1993-07-23

1997-05-13

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514913, A61K 31175

Patent

active

056293453

ABSTRACT:
ATP-sensitive K.sup.+ channel modulating compounds are incorporated into ophthalmically acceptable carriers for administration to the eye in order to affect intraocular pressure. Such formulations including compounds which inhibit the channel are particularly suitable for treating glaucoma and other disorders related to elevated intraocular pressure. Such formulation which potentiates the channel are particularly suitable for treating hypotonia and other depressed intraocular pressure conditions.

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