Methods and compositions for assessing acute rejection

Details Methods and compositions for assessing acute rejection Methods and compositions for assessing acute rejection

2007-03-13

2010-10-12

Martinell, James (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100

Reexamination Certificate

active

07811767

ABSTRACT:
The invention relates to the analysis and identification of genes that are up-regulated simultaneously in transplant rejection. This simultaneous up-regulation of genes provides a molecular signature to accurately detect transplant rejection.

REFERENCES:
patent: 5962301 (1999-10-01), Horvitz et al.
patent: 1 780 542 (2007-05-01), None
patent: 2004/018710 (2004-03-01), None
patent: 2005/054503 (2005-06-01), None
patent: 2005/117943 (2005-12-01), None
patent: 2006/003927 (2006-01-01), None
patent: 2006/125301 (2006-11-01), None
Inkinen et al., “DNA Microarray-Based Gene Expression Profiles of Cytomegalovirus Infection and Acute Rejection in Liver Transplants”, Transplantation Proceedings, vol. 37, No. 2, pp. 1227-1229, (2005).
Flechner S M et al., “Kidney Transplant Rejection and Tissue Injury by Gene Profiling of Biopsies and Peripheral Blood Lymphocytes”, American Journal of Transplantation, vol. 4, No. 9, pp. 1475-1489, (2004).
Akalin E et al., “Gene Expression Analysis In Human Renal Allograft Biopsy Samples Using High-Density Oligoarray Technology”, Transplantation, vol. 72, No. 5, pp. 948-953, (2001).
Sarwal M et al., “Molecular Heterogeneity in Acute Renal Allograft Rejection Identified by DNA Microarray Profiling”, New England Journal of Medicine, vol. 349, No. 2, pp. 125-138, (2003).

Affiliated with

Also associated with

Rating

Methods and compositions for assessing acute rejection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and compositions for assessing acute rejection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for assessing acute rejection will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4217910