Methods and compositions employing interferon-gamma

Details Methods and compositions employing interferon-gamma Methods and compositions employing interferon-gamma

1990-05-23

1992-01-21

Doll, John

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

424 854, 424 856, 424 857, A61K 3766

Patent

active

050826590

ABSTRACT:
The present disclosure is directed to improved pharmaceutical compositions employing inteferon-gamma which have been treated to remove interferon-gamma inhibitory activity associated with such preparations. In addition, the present disclosure details treatment protocols, including the elevation of patient body temperature and the use of combined or sequential interferon-gamma treatments, to enhance inteferon-gamma efficacy and reduce the resistance associated with inteferon-alpha and/or beta therapy.

REFERENCES:
Weigent et al. Inf. & Imm., vol. 40, No. 1, pp. 35-38, Apr. 1983.
Fleischmann Inf. & Imm., vol. 26, No. 1, pp. 248-253, Oct. 1979.

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