Methods and compositions employing 2,4-dienoic acid esters of to

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31355

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active

059227583

ABSTRACT:
The subject invention involves methods and compositions for reducing non-ultraviolet-induced free radical damage in mammals comprising administering to a mammal a composition comprising a safe and effective amount of a compound selected from 2,4-dienoic acid esters of tocopherols and mixtures of such compounds, optionally in combination with chelating agents and/or anti-inflammatory agents.

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Buettner et al., :Ascorbate Free Radical as a Marker of Oxidative Stress: An EPR Study, Free Radical Biology Medicine, vol. 14 pp.49-55(1993).

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