Compositions: ceramic – Ceramic compositions – Glass compositions – compositions containing glass other than...
Patent
1997-06-03
1999-12-14
Koslow, C. Melissa
Compositions: ceramic
Ceramic compositions
Glass compositions, compositions containing glass other than...
501 1, 423305, 423306, 423301, 423430, 423497, 423464, C01F 1118, C01F 1122, C01B 2532
Patent
active
060003413
ABSTRACT:
This invention involves new compositions and methods of use and delivery of amorphous calcium compounds such as: amorphous calcium phosphate (ACP), amorphous calcium phosphate fluoride (ACPF), amorphous calcium carbonate phosphate (ACCP), amorphous calcium carbonate phosphate fluoride (ACCPF), and amorphous calcium fluoride (ACF) for use in remineralizing and fluoridating teeth. These amorphous compounds or solutions which form the amorphous compounds or calcium phosphate jelly which forms the amorphous compounds, when applied either onto or into dental tissue to prevent and/or repair dental weaknesses such as dental caries, exposed roots and dentin sensitivity. The compounds have the highest solubilities, fastest formation rates and fastest conversion rates (to apatite) among all the calcium phosphates under physiological conditions. Moreover, in the presence to fluoride the amorphous compound convert rapidly to fluoride containing apatite.
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Lerner et al, "Rapid Percipitation of Apatite from Ethanol-Water Solution", J. Cryst. Growth, 97(3-4), 725-30, Oct. 1989.
Tung et al, "Effect of Ethanol on the Formation of Calcium Phosphates", Colloids and Surfaces A, vol. 110, pp. 191-98, 1996.
Kamiya et al, "Aragonite Formation Through Precipitation of Calcium Carbonate Monohydrate", Mat. Res. Bull., vol. 12, No. 11, pp. 1095-102, Nov. 1977.
Chemical Abstracts citation 112:90216: Astrelin et al, "Prepartion of Fluorohydroxycarbonate Apatites and Calculation of the Kinetic Parameters of Their Thermolysis", Zh. Neorg. Khim., vol. 34 (10), pp. 2587-2592, 1989 .
American Dental Association - Health Foundation
Koslow C. Melissa
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