Methods and composition for identifying group a streptococcus

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

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4241651, 4242441, 435 4, 435 6, 435 734, 435 74, 435 792, 435 36, 4352534, 435340, C12N 506, A61K 3940, A61K 3909, C12Q 100

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060308354

ABSTRACT:
Methods and compositions are provided for identifying a group A Streptococcus in any of a variety of physiological samples, such as blood, saliva, throat swabs, cerebrospinal fluid, brocheolar lavage material, and biopsy material. The positions used include an extracellular cysteine protease or a fragment thereof, obtainable from S. pyogenes and containing at least one conserved epitope, or nucleic acid encoding the cysteine protease or fragment thereof. The compositions also find use in eliciting a protective immune response against a group A streptococcus infection.

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