Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1995-06-02
1997-08-26
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
5147723, 514781, A61F 202, A61K 4730
Patent
active
056608462
ABSTRACT:
The invention features an implantable device for the automatic delivery of an active ingredient according to an adjustable delivery profile. The device includes a housing; a reservoir operatively connected to the housing and arranged to store a solid composition including the active ingredient; an actuator arranged within the housing to move the solid composition from the reservoir to a transit area, wherein the solid composition exits the housing at the transit area; a controller that acts on the actuator to adjust movement of the solid composition out of the housing according to the adjustable delivery profile; and a power source arranged to provide energy to the actuator and the controller. The solid composition can be an elongate, solid composition comprising a drug, and up to 90% of a carrier, wherein the composition has a cross-section of less than 0.5 mm, and wherein the drug and the carrier are selected and compounded in a proportion such that the drug is immediately released from the carrier upon contact with a liquid.
REFERENCES:
patent: 2513014 (1950-06-01), Fields
patent: 3692027 (1972-09-01), Ellinwood, Jr.
patent: 3760806 (1973-09-01), Leeper
patent: 3995631 (1976-12-01), Higuchi et al.
patent: 3995632 (1976-12-01), Nakano et al.
patent: 4086914 (1978-05-01), Moore
patent: 4093708 (1978-06-01), Zaffaroni et al.
patent: 4177256 (1979-12-01), Michaels et al.
patent: 4263910 (1981-04-01), Pardekooper et al.
patent: 4327725 (1982-05-01), Cortese et al.
patent: 4340054 (1982-07-01), Michaels
patent: 4344743 (1982-08-01), Bessman et al.
patent: 4360019 (1982-11-01), Portner et al.
patent: 4451253 (1984-05-01), Harman
patent: 4581018 (1986-04-01), Jassawalla et al.
patent: 4595583 (1986-06-01), Eckenhoff et al.
patent: 4596575 (1986-06-01), Rosenberg et al.
patent: 4661103 (1987-04-01), Harman
patent: 4711251 (1987-12-01), Stokes
patent: 4720384 (1988-01-01), Di Luccio et al.
patent: 4723958 (1988-02-01), Pope et al.
patent: 4753636 (1988-06-01), Free
patent: 4772263 (1988-09-01), Dorman et al.
patent: 4834704 (1989-05-01), Reinicke
patent: 4886514 (1989-12-01), Maget
patent: 4888074 (1989-12-01), Pocknell
patent: 4900304 (1990-02-01), Fujioka et al.
patent: 4936827 (1990-06-01), Grimm et al.
patent: 4941874 (1990-07-01), Sandow et al.
patent: 4944659 (1990-07-01), Labbe et al.
patent: 4976966 (1990-12-01), Theeuwes et al.
patent: 4994028 (1991-02-01), Leonard et al.
patent: 5030216 (1991-07-01), Theuuwes et al.
patent: 5049141 (1991-09-01), Olive
patent: 5086787 (1992-02-01), Grandjean et al.
patent: 5112614 (1992-05-01), Magruder et al.
patent: 5226895 (1993-07-01), Harris
patent: 5350741 (1994-09-01), Takada
Campfield et al., Chemical Abstracts, vol. 115, #99281.
Azpuru Carlos A.
Societe de Conseils de Recherches et d'Applications Scientifique
LandOfFree
Methods and apparatus for the delivery of solid drug composition does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and apparatus for the delivery of solid drug composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and apparatus for the delivery of solid drug composition will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1986453