Methods and apparatus for sequencing polymers with a statistical

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 911, 435 912, 435 18, 435 4, 422 62, 422 50, 364496, 364497, 364498, 364499, 530300, 530350, 536 231, 536 243, C12Q 168, G06F 1546, G06G 758, C07K 500

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058692401

ABSTRACT:
Integrated methods and apparatus for sequencing or identifying polymers by mass spectrometry with a statistical certainty. The methods involve integrating data obtained by mass spectrometry analysis of a series of polymer fragments and statistically comparing said data with hypothetical data corresponding to known sequences or identities.

REFERENCES:
patent: 5064754 (1991-11-01), Mills
patent: 5100778 (1992-03-01), Rademacher et al.
patent: 5221518 (1993-06-01), Mills
patent: 5382513 (1995-01-01), Lam et al.
patent: 5622824 (1997-04-01), Koster
Chait et al. Science 262:89-92, 1993.
Bartlett-Jones et al. Rapid Comm. in Mass Spectrometry,8: 737-742, 1994.
Jue et al. Biochemistry 24: 162-70, 1985.
Eberhard, In Biology Laboratory,CBS College Publishing, Appendix B, 1987.
R.J. Colton, "Secondary Ion Mass Spectrometry: High-Mass Molecular and Cluster Ions" Nucl. Instr. and Methods in Physics Res. 218:276-286 (1983).
J.G. Van Raaphorst et al., "The Evaluation of Measurement Data in Thermal Ionisation Mass Spectrometry" Intl. J. of Mass Spectrometry and Ion Physics 31:65-69 (1979).
P. Roepstorff, "Mass Spectrometry of Proteins" TRAC: Trends in Analytical Chemistry 12(10):413-421 (1993).
Abstract: Database WPI, Section Ch. Week 9018, Derwent Publications Ltd., London, GB, Class BO4, AN 90-137766, XPOO2014080 & SU,A,1 514 782 (1988).
International Search Report of corresponding PCT Application No. PCT/US96/07146 dated Oct. 4, 1996.

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