Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-05-19
1999-02-09
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 435 912, 435 18, 435 4, 422 62, 422 50, 364496, 364497, 364498, 364499, 530300, 530350, 536 231, 536 243, C12Q 168, G06F 1546, G06G 758, C07K 500
Patent
active
058692401
ABSTRACT:
Integrated methods and apparatus for sequencing or identifying polymers by mass spectrometry with a statistical certainty. The methods involve integrating data obtained by mass spectrometry analysis of a series of polymer fragments and statistically comparing said data with hypothetical data corresponding to known sequences or identities.
REFERENCES:
patent: 5064754 (1991-11-01), Mills
patent: 5100778 (1992-03-01), Rademacher et al.
patent: 5221518 (1993-06-01), Mills
patent: 5382513 (1995-01-01), Lam et al.
patent: 5622824 (1997-04-01), Koster
Chait et al. Science 262:89-92, 1993.
Bartlett-Jones et al. Rapid Comm. in Mass Spectrometry,8: 737-742, 1994.
Jue et al. Biochemistry 24: 162-70, 1985.
Eberhard, In Biology Laboratory,CBS College Publishing, Appendix B, 1987.
R.J. Colton, "Secondary Ion Mass Spectrometry: High-Mass Molecular and Cluster Ions" Nucl. Instr. and Methods in Physics Res. 218:276-286 (1983).
J.G. Van Raaphorst et al., "The Evaluation of Measurement Data in Thermal Ionisation Mass Spectrometry" Intl. J. of Mass Spectrometry and Ion Physics 31:65-69 (1979).
P. Roepstorff, "Mass Spectrometry of Proteins" TRAC: Trends in Analytical Chemistry 12(10):413-421 (1993).
Abstract: Database WPI, Section Ch. Week 9018, Derwent Publications Ltd., London, GB, Class BO4, AN 90-137766, XPOO2014080 & SU,A,1 514 782 (1988).
International Search Report of corresponding PCT Application No. PCT/US96/07146 dated Oct. 4, 1996.
Jones W. Gary
PerSeptive Biosystems Inc.
Rees Dianne
LandOfFree
Methods and apparatus for sequencing polymers with a statistical does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and apparatus for sequencing polymers with a statistical, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and apparatus for sequencing polymers with a statistical will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1947531