Methods and apparatus for isolating platelets from blood

Liquid purification or separation – Processes – Separating

Reexamination Certificate

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C210S109000, C210S121000, C210S512100, C210S516000, C210S518000, C210S361000, C210S789000, C422S105000, C422S918000, C436S177000, C494S016000, C494S037000, C494S038000, C494S045000, C494S056000

Reexamination Certificate

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07470371

ABSTRACT:
A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Platelets are then removed from the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.

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