Methods and apparatus for genotyping

Details Methods and apparatus for genotyping Methods and apparatus for genotyping

2007-11-09

2011-10-04

Lin, Jerry (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

Reexamination Certificate

active

08032307

ABSTRACT:
A method for establishing the genotype of the locus is provided in which a series of calibration samples are analysed, the results being one of three indication types, a window being defined relative to the indication for each of the indication types, unknown samples being similarly analysed with the window that they fall within being taken to determine the indication type for the unknown sample and hence the genotype of the relevant locus. The technique provides a robust, reliable and accurate method of genotyping which is suited to automation.

REFERENCES:
patent: 6342355 (2002-01-01), Hacia et al.
patent: 2002/0016680 (2002-02-01), Wang et al.
patent: WO 02/03849 (2002-01-01), None
Sohni et al., “Active electronic arrays for genotyping of NAT2 polymorphisms,”Clinical Chemistry(2001) 47 (10): 1922-1924.
Gill et al., “A new method of STR interpretation using inferential logic—development of a criminal intelligence database,”International Journal of Legal Medicine(1996) 109: 14-22. XP001104965.
International Search Report for corresponding International Application PCT/GB2003/01489 mailed May 6, 2004.

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