Surgery – Diagnostic testing – Cardiovascular
Reexamination Certificate
2006-02-21
2010-02-23
Marmor, II, Charles A (Department: 3735)
Surgery
Diagnostic testing
Cardiovascular
Reexamination Certificate
active
07666144
ABSTRACT:
Method and apparatus are introduced for determining proportional cardiac output (CO), absolute left atrial pressure (LAP), and/or other important hemodynamic variables from a contour of a circulatory pressure waveform or related signal. Certain embodiments of the invention provided herein include the mathematical analysis of a pulmonary artery pressure (PAP) waveform or a right ventricular pressure (RVP) waveform in order to determine beat-to-beat or time-averaged proportional CO, proportional pulmonary vascular resistance (PVR), and/or LAP. The invention permits continuous and automatic monitoring of critical hemodynamic variables with a level of invasiveness suitable for routine clinical application. The invention may be utilized, for example, to continuously monitor critically ill patients with pulmonary artery catheters installed and chronically monitor heart failure patients instrumented with implanted devices for measuring RVP.
REFERENCES:
patent: 6506163 (2003-01-01), Farrell et al.
patent: 7398688 (2008-07-01), Zdeblick et al.
Cohen Richard J.
Mukkamala Ramakrishna
Board of Trustees Operating - Michigan State University
Harness & Dickey & Pierce P.L.C.
Jang Christian Y
Marmor II Charles A
Massachusetts Institute of Technology
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