Methods and apparatus for detection of molecular chirality

Details Methods and apparatus for detection of molecular chirality Methods and apparatus for detection of molecular chirality

2008-05-20

2008-05-20

Wu, Shean C (Department: 1795)

Chemistry: analytical and immunological testing

Optical result

C436S149000, C436S805000, C436S806000, C252S299010, C252S299500

Reexamination Certificate

active

07374948

ABSTRACT:
The disclosure provides methods for the determination of the enantiomeric excess of chiral compounds. The methods involve doping a chiral analyte into an achiral liquid crystal host to form a chiral dopant/host liquid crystal mixture. An electro-optic signature of the mixture is then determined and is used to calculate the enantiomeric excess of the chiral analyte. The disclosure also provides systems for performing the disclosed methods of determining enantiomeric excess.

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