Methods and apparatus for creating particle derivatives of...

Details Methods and apparatus for creating particle derivatives of... Methods and apparatus for creating particle derivatives of...

2008-03-24

2011-11-01

Kam, Chih-Min (Department: 1656)

Surgery

Blood drawn and replaced or treated and returned to body

Constituent removed from blood and remainder returned to body

C514S002600, C514S012200, C530S359000, C424S491000, C210S749000

Reexamination Certificate

active

08048015

ABSTRACT:
The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol levels in cells, tissues, organs, and blood vessels. The present method is useful for treating atherogenic vascular disease and may be combined with other therapies such as statins, inhibitors of cholesterol absorption, niacin, anti-inflammatories, exercise and dietary restriction.

REFERENCES:
patent: 3647624 (1972-03-01), Evenson
patent: 3958939 (1976-05-01), Jones
patent: 3983008 (1976-09-01), Shinozaki et al.
patent: 3989466 (1976-11-01), Pan
patent: 4025423 (1977-05-01), Stonner et al.
patent: 4103685 (1978-08-01), Lupien et al.
patent: 4124509 (1978-11-01), Iijima et al.
patent: 4234317 (1980-11-01), Lucas et al.
patent: 4235602 (1980-11-01), Meyer et al.
patent: 4258010 (1981-03-01), Rozsa et al.
patent: 4311586 (1982-01-01), Baldwin et al.
patent: 4350156 (1982-09-01), Malchesky et al.
patent: 4391711 (1983-07-01), Jackson et al.
patent: 4399217 (1983-08-01), Holmquist et al.
patent: 4402940 (1983-09-01), Nose et al.
patent: 4435289 (1984-03-01), Breslau
patent: 4463988 (1984-08-01), Bouck et al.
patent: 4481189 (1984-11-01), Prince
patent: 4522809 (1985-06-01), Adamowicz et al.
patent: 4540401 (1985-09-01), Marten
patent: 4540573 (1985-09-01), Neurath et al.
patent: 4591505 (1986-05-01), Prince
patent: 4613501 (1986-09-01), Horowitz
patent: 4615886 (1986-10-01), Purcell et al.
patent: 4643718 (1987-02-01), Marten
patent: 4645512 (1987-02-01), Johns
patent: 4647280 (1987-03-01), Maaskant et al.
patent: 4648974 (1987-03-01), Rosskopf et al.
patent: 4668398 (1987-05-01), Silvis
patent: 4671909 (1987-06-01), Torobin
patent: 4676905 (1987-06-01), Nagao et al.
patent: 4677057 (1987-06-01), Curtiss et al.
patent: 4680320 (1987-07-01), Uku et al.
patent: 4696670 (1987-09-01), Ohnishi et al.
patent: 4775483 (1988-10-01), Mookerjea et al.
patent: 4832034 (1989-05-01), Pizziconi et al.
patent: 4836928 (1989-06-01), Aoyagi et al.
patent: 4879037 (1989-11-01), Utzinger
patent: 4895558 (1990-01-01), Cham
patent: 4908354 (1990-03-01), Seidel et al.
patent: 4909940 (1990-03-01), Horowitz et al.
patent: 4909942 (1990-03-01), Sato et al.
patent: 4923439 (1990-05-01), Seidel et al.
patent: 4935204 (1990-06-01), Seidel et al.
patent: 4966709 (1990-10-01), Nose et al.
patent: 4970144 (1990-11-01), Fareed et al.
patent: 5026479 (1991-06-01), Bikson et al.
patent: 5055396 (1991-10-01), Curtiss et al.
patent: 5080796 (1992-01-01), Nose et al.
patent: 5089602 (1992-02-01), Isliker et al.
patent: 5112956 (1992-05-01), Tang et al.
patent: 5116307 (1992-05-01), Collins
patent: 5126240 (1992-06-01), Curtiss
patent: 5128318 (1992-07-01), Levine et al.
patent: 5152743 (1992-10-01), Gorsuch et al.
patent: 5187010 (1993-02-01), Parham et al.
patent: 5203778 (1993-04-01), Boehringer et al.
patent: 5211850 (1993-05-01), Shettigar et al.
patent: 5236644 (1993-08-01), Parham et al.
patent: 5256767 (1993-10-01), Salk et al.
patent: 5258149 (1993-11-01), Parham et al.
patent: 5279540 (1994-01-01), Davidson
patent: 5301694 (1994-04-01), Raymond et al.
patent: 5354262 (1994-10-01), Boehringer et al.
patent: 5391143 (1995-02-01), Kensey
patent: 5393429 (1995-02-01), Nakayama et al.
patent: 5401415 (1995-03-01), Rauh et al.
patent: 5401466 (1995-03-01), Foltz et al.
patent: 5418061 (1995-05-01), Parham et al.
patent: 5419759 (1995-05-01), Naficy
patent: 5424068 (1995-06-01), Filip
patent: 5476715 (1995-12-01), Otto
patent: 5484396 (1996-01-01), Naficy
patent: 5496637 (1996-03-01), Parham et al.
patent: 5523096 (1996-06-01), Okarma et al.
patent: 5529933 (1996-06-01), Young
patent: 5634893 (1997-06-01), Rishton
patent: 5637224 (1997-06-01), Sirkar et al.
patent: 5652339 (1997-07-01), Lerch et al.
patent: 5679260 (1997-10-01), Boos et al.
patent: 5698432 (1997-12-01), Oxford
patent: 5707673 (1998-01-01), Prevost et al.
patent: 5719194 (1998-02-01), Mann et al.
patent: 5744038 (1998-04-01), Cham
patent: 5753227 (1998-05-01), Strahilevitz
patent: 5853725 (1998-12-01), Salk et al.
patent: 5855782 (1999-01-01), Falkenhagen et al.
patent: 5858238 (1999-01-01), McRea et al.
patent: 5877005 (1999-03-01), Castor et al.
patent: 5885578 (1999-03-01), Salk et al.
patent: 5895650 (1999-04-01), Salk et al.
patent: 5911698 (1999-06-01), Cham
patent: 5916806 (1999-06-01), Salk et al.
patent: 5919369 (1999-07-01), Ash
patent: 5928930 (1999-07-01), Salk et al.
patent: 5948441 (1999-09-01), Lenk et al.
patent: 5962322 (1999-10-01), Kozarsky et al.
patent: 5980478 (1999-11-01), Gorsuch et al.
patent: 6004925 (1999-12-01), Dasseux et al.
patent: 6017543 (2000-01-01), Salk et al.
patent: 6022333 (2000-02-01), Kensey
patent: 6037323 (2000-03-01), Dasseux et al.
patent: 6037458 (2000-03-01), Hirai et al.
patent: 6039946 (2000-03-01), Strahilevitz
patent: 6046166 (2000-04-01), Dasseux et al.
patent: 6080778 (2000-06-01), Yankner et al.
patent: 6127370 (2000-10-01), Smith et al.
patent: 6136321 (2000-10-01), Barrett et al.
patent: 6139746 (2000-10-01), Kopf
patent: 6156727 (2000-12-01), Garber et al.
patent: 6171373 (2001-01-01), Park et al.
patent: 6193891 (2001-02-01), Kent et al.
patent: 6264623 (2001-07-01), Strahilevitz
patent: 6309550 (2001-10-01), Iverson et al.
patent: 6337368 (2002-01-01), Kobayashi et al.
patent: RE37584 (2002-03-01), Cham
patent: 6440387 (2002-08-01), Yankner et al.
patent: 6472421 (2002-10-01), Wolozin
patent: 6605588 (2003-08-01), Lees et al.
patent: 6706008 (2004-03-01), Vishnoi et al.
patent: RE39498 (2007-02-01), Cham et al.
patent: 7361739 (2008-04-01), Bellotti et al.
patent: 7375191 (2008-05-01), Bellotti et al.
patent: 7393826 (2008-07-01), Bellotti et al.
patent: 2001/0028895 (2001-10-01), Bisgaier et al.
patent: 2002/0055529 (2002-05-01), Bisgaier et al.
patent: 2002/0081263 (2002-06-01), Yankner et al.
patent: 2002/0107173 (2002-08-01), Friedhoff et al.
patent: 2002/0128581 (2002-09-01), Vishnoi et al.
patent: 2002/0183379 (2002-12-01), Yankner et al.
patent: 2002/0188012 (2002-12-01), Bisgaier et al.
patent: 2003/0018013 (2003-01-01), Dasseux et al.
patent: 2003/0127390 (2003-07-01), Davis, Jr.
patent: 2004/0106556 (2004-06-01), Zhu et al.
patent: 2008/0214438 (2008-09-01), Bellotti et al.
patent: 2008/0234621 (2008-09-01), Bellotti et al.
patent: 1 271 708 (1990-07-01), None
patent: 1189378 (1998-08-01), None
patent: 29 44 138 (1981-06-01), None
patent: 31 18 072 (1982-11-01), None
patent: 32 13 390 (1983-10-01), None
patent: 33 10 263 (1984-09-01), None
patent: 0 036 283 (1981-09-01), None
patent: 0 267 471 (1988-05-01), None
patent: 2 571 971 (1986-04-01), None
patent: 127104 (1980-01-01), None
patent: 277303 (1993-10-01), None
patent: 1116396 (1984-09-01), None
patent: 1204224 (1986-01-01), None
patent: 1752187 (1990-12-01), None
patent: WO 8809345 (1988-12-01), None
patent: WO 95/03840 (1995-02-01), None
patent: WO 99/38498 (1999-08-01), None
patent: WO 01/45718 (2001-06-01), None
patent: WO 01/56579 (2001-08-01), None
patent: 02/00266 (2002-01-01), None
patent: WO 02/10768 (2002-02-01), None
patent: WO 02/30863 (2002-04-01), None
patent: WO 02/062824 (2002-08-01), None
patent: 03/000372 (2003-01-01), None
patent: WO 03/000373 (2003-01-01), None
U.S. Appl. No. 12/042,881, filed Mar. 5, 2008, Bellotti et al.
U.S. Appl. No. 12/054,088, filed Mar. 24, 2008, Bellotti et al.
U.S. Appl. No. 12/203,551, filed Sep. 3, 2008, Zhu et al.
Agnese et al., Evaluation of Four Reagents for Delipidation of Serum,Clinical Biochemistry, v. 16, 98-100 (1983).
Albouz et al., Extraction of Plasma Lipids Preserving Antigenic Properties of Proteins and Allowing Quantitation of Gangliosides by Neuraminic Acid Determination,Ann. Biol. Clin., v. 37, 287-290 (abstract only) (1979).
André et al., Characterization of Low- and Very-Low-Density Hepatitis C Virus RNA-Containing Particles,Journal of Virology, v.

Affiliated with

Also associated with

Rating

Methods and apparatus for creating particle derivatives of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and apparatus for creating particle derivatives of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and apparatus for creating particle derivatives of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4309949