Methods and apparatus for analyzing nucleic acid molecules

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 5, 435 911, 435291, 435 29, 435 34, 4352871, 4352882, 436 94, C12Q 168, C12Q 170, C12P 1934, G01N 3300

Patent

active

057562970

ABSTRACT:
A sample containing nucleic acid molecules is mixed with a same volume of reagent such as isopropanol to render the nucleic acid molecules insoluble. This solution containing the nucleic acid molecules in insoluble condition is introduced into a flow cell and exposed therein to light from a light source. Scattered light from the nucleic acid molecules is detected by light sensors and analyzed by a computer.

REFERENCES:
patent: 4500641 (1985-02-01), Van Den Engh
Haussmann et al. Z. Naturforsch Sect C. Biosci 46: 433-442, 1991.

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