Methods and apparatus for analyzing electrophoresis gels

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

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204612, 382129, G01N27/26

Patent

active

059048220

ABSTRACT:
This invention relates to a system and methods for the straightening an electrophoresis gel image in the vertical and horizontal directions, and for analyzing a straightened gel image. The system includes an input unit for receiving raw data from the electrophoresis gel, a straightening unit for providing a straightened gel image, an output unit for portraying the raw data from the electrophoresis gel and the straightened gel image, and a an analyzing unit for analyzing the data portrayed in the straightened gel image. The system features a dye boost feature for boosting the intensity of bands, filtering means for modifying the gel image, and a genotype editing feature for editing the results of an automatic gel analysis. The system allows for manual and automatic analysis of the straightened gel image according to a specified set of analysis parameters providing a range of analysis stringency levels.

REFERENCES:
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CAPLUS abstract of Metzker et al. (Accurate determination of DNA in agarose gels using the novel algorithm GelScann(1.0), Comput. Appl. Biosci. (1995), 11(2), 17-94), 1995 Month Unavailable.
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