Methods and agents for the prophylaxis of atopy

Details Methods and agents for the prophylaxis of atopy Methods and agents for the prophylaxis of atopy

1995-04-11

1997-01-07

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

426648, 426801, 514558, 514560, A61K 3120

Patent

active

055914462

ABSTRACT:
A method for atopy prophylaxis involves administering an agent comprising .gamma.-linolenic acid, dihomo-.gamma.-linolinic acid, the physiologically compatible salts, esters, amides, phospholipids, glycolipids thereof, and/or prostaglandin E.sub.1 (PGE.sub.1), PGE.sub.1 derivatives, PGE.sub.1 analogs to preimmunocompetent humans to prevent the occurrence of atopy. These agents are typically contained in a baby food or are supplied to the baby concurrently. These foods may contain one or more thymus hormones. The use of PGE.sub.1, its derivatives and analogs and the physiologically compatible esters, amides, phospholipids and glycolipids thereof in a pharmacologically effective dosage form for the topical or inhalative treatment of acute manifest atopy in the dermal and mucosal areas. These substances are preferably used in combination with .gamma.-linolinic acid, and dihomo-.gamma.-linolinic acid, and/or the physiologically compatible salts, esters, amides, phospholipids and glycolipids thereof.

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