Methods, agents and kits for detection of organophosphorus compo

Details Methods, agents and kits for detection of organophosphorus compo Methods, agents and kits for detection of organophosphorus compo

1998-05-01

2000-10-17

Swartz, Rodney P.

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

435 792, 435 793, 436547, 436548, 5303889, G01N 33531, G01N 3353, C07K 1600

Patent

active

061330493

ABSTRACT:
Novel generic antibodies are provided that are specific to groups of organophosphates, particularly to a class of organophosphate pesticides in common usage. Further provided are compounds and methods for raising these antibodies, test kits containing them and methods for their use. The antibodies targeted at low molecular weight (i.e. below MW 1000) organophosphorous pesticides methacrifos, pirimphos methyl, etrimfos, fenitrothion, chlopyrifos methyl, dichlorovos and malathion. Preferred conjugates of the invention are of the formula (RO.sub.2 --P(S)--Z--[Y]--Protein wherein R is lower alkyl and Z is as O, S or --NH--, Y is a spacer group and "Protein" indicates a protein suitable for use in hapten protein conjugates for the purpose of raising antibodies and antisera. Typical and preferred proteins are bovine serum albumin, ovalbumin from chicken egg, keyhole limpet hemocyananin and mixtures of these.

REFERENCES:
patent: 5283180 (1994-02-01), Zomer et al.
patent: 5413915 (1995-05-01), Case et al.
patent: 5589624 (1996-12-01), Ulbrich et al.
patent: 5830770 (1998-11-01), Matthews et al.

Affiliated with

Also associated with

Rating

Methods, agents and kits for detection of organophosphorus compo does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods, agents and kits for detection of organophosphorus compo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods, agents and kits for detection of organophosphorus compo will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-467515