Method using snail transcriptional repressor

Details Method using snail transcriptional repressor Method using snail transcriptional repressor

2006-08-25

2011-10-04

Aeder, Sean (Department: 1642)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100

Reexamination Certificate

active

08029989

ABSTRACT:
Provided is a prognostic molecular marker for breast cancer recurrence. Expression of Snail, a zinc finger transcriptional repressor gene, is correlated to the risk of breast cancer recurrence, and to the likelihood of recurrence-free survival in subjects diagnosed with breast cancer. Further provided are methods of identifying therapeutic compositions for treating breast cancer to reduce recurrence associated with high expression of Snail, and methods of controlling Snail expression for research and therapeutic purposes.

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