Method to treat endotoxin effects by administration of 33 kiloda

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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A61K 3817

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active

056588771

ABSTRACT:
Pharmaceutical compositions containing safe and effective amounts of Annexin I or 33 kDa(PLBP) can be used in a number of methods for the benefit of animals.

REFERENCES:
patent: 5201308 (1993-04-01), Newhouse
patent: 5225183 (1993-07-01), Purewal et al.
patent: 5238683 (1993-08-01), Crystal
patent: 5298489 (1994-03-01), Wallner et al.
patent: 5302581 (1994-04-01), Sarin et al.
patent: 5314890 (1994-05-01), Agostini et al.
patent: 5314992 (1994-05-01), Guyre et al.
patent: 5316915 (1994-05-01), Kraus et al.
patent: 5384128 (1995-01-01), Meezen et al.
Lacht et al. (1988) Am. J. Med. Sci. 296, 88-102.
Reutelingsperger et al., FEBS Letters 349 (1994), pp. 120-124 "Differential tissue expression of Annexin VIII in human."
Tsao FHC, et al., Biochim. Biophys. Acta 1213, 91-99 (1994) "Immunocharacterization and developmental regulation of rabbit lung calcium-dependent phospholipid-binding proteins."
Strijbos et al., Am. J. Physiol (1993) E289-E297, "Impaired febrile responses of aging mice are mediated by endogenous lipocortin-1 (annexin-1)".
Strijbos et al., Am. J. Physiol 263, (1992) E632-E636, "Inhibition of central actions of cytokines on fever and thermogenesis by lipocortin-1 involves CRF".
Das SK et al., Mol. Cellul. Biochem, 115, (1992) pp. 79-84, "Identification of calcium-dependent phospholipid-binding proteins (annexins) from guinea pig alveolar type II cells."
Keith et al., FASEB J. vol. 6 No. 4 Feb. 26, 1992, p. A1162, "Localization of phospholipid binding protein in rabbit lung".
Ambrose et al., American Journal of Respirory Cell and Molecular Biology, vol. 6 (1992) pp. 17-21, "Lipocortin I Production by Human Alveolar Macrophages."
Chung et al., Respiratory Medicine 85, 1991, 121-124 "Circulating autoantibodies to recombinant lipocortin-1 in asthma".
Perretti et al., Journal of Immunology, vol. 151, 1991 pp. 4307-4314, "Lipocortin-1 Fragments Inhibit Neutrophil Accumulation and Neutrophil-Dependent Edema in the Mouse".
Tsao FHC et al., "Lung calcium-dependent phospholipid-binding proteins: structure and function" Biochim. Biophys Acta 1081, 1991, 141-150.
Strijbos et al., American Journal of Physiological Society (1990) 11p, "Central and Peripheral Actions of Recombinant Lipocortin-1 and a Fragment of Lipocortin-1 on the Responses to Interleukin-1B".
Smith et al., Environmental Health Perspective vol. 85, 1990, pp. 135-144, "Detection of Lipocortin 1 in Human Lung Lavage Fluid; Lipocortin Degradation As a Possible Proteolytic Mechanism in the Control of Inflammatory Mediators and Inflammation".
Tsao FHC, Biochimica et Biophysica Acta. 1045 (1990) p29-39, "Purification and characterization of two rabbit lung Ca.sup.2+ -dependent phospholipid-binding proteins".
Ambrose et al., Am. J. Respir. Cell Mol. Biol. vol. 3, 1990, pp. 349-353, "Corticosteroids Increase Lipocortin I in Alveolar Epithelial Cells".
Ambrose et al., Am. J. Respir. 1990, pp. 1668-1671, "Corticosteroids increase Lipocortin I in BAL fluid from normal individuals and patients with lung disease".
Carey et al., J. Physiol 1990, R266-R269, "Lipocortin 1 fragment modifies pyrogenic actions of cytokines in rats".
Sakata et al., The Journal of Immunology vol. 145, No. 1, 1990 387-396 "The Role of Lipocortin I in Macrophage-Mediated Immunosuppresion in Tumor-Bearing Mice".
Davidson J., et al. Br. J. Pharmacol. 102, (1991) pp. 7-9, "Antipyretic actions of human recombinant lipocortin-1."
Maridonneau-Parini, I, et al. J. Clin. Invest. 83, (1989) pp. 1936-1940, "Inhibtion of O2 generation by dexamethasone is mimicked by lipocortin I in alveolar macrophages."
Perretti, M. et al. Pharmacol. Res. 30, (1994) pp. 53-59, "Cytokines, glucocorticoids and lipocortins in the control of neutrophil migration."
Cirino, G. et al. Proc. Natl. Acad, Sci. USA. 86, (1989) pp. 3428-3432, "Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test."
Relton, J. K. et al. J. Exp. Med. 174, (1991) pp. 305-310, "Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain."
Chung, K. F., et al. Respir. Med. 85, (1991) pp. 121-124, "Circulating autoantibodies to recombinant lipocortin-1 in asthma."
Perretti, M., et al. Br. J. Pharmacol. 103, (1991) pp. 1327-1332, "A novel anti-inflammatory peptide from human lipocortin 5."
Smith, S. F., et al. 151(4), (1995) p. A484, "Comparison of lipocortin 1 in human bronchoalveolar lavage (BAL) cells ex vivo and in vitro."
Drost, E. M., et al. 151(4), (1995) p. A453, "Effect of lipocortin 1 (Lcl) on human polymorphonuclear neutrophil (PMN) deformability."
Tsao, F. H. C., et al. 151(4), (1995) p. A741, "Structure and function of annexin I in human bronchoalveolar lavage fluid."

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