Coating processes – Medical or dental purpose product; parts; subcombinations;... – Flexible web – sheet – film – or filament base
Patent
1994-06-08
1995-08-15
Dudash, Diana
Coating processes
Medical or dental purpose product; parts; subcombinations;...
Flexible web, sheet, film, or filament base
427 228, 427 225, 427551, B05D 306, B05D 118, B05D 302
Patent
active
054417597
ABSTRACT:
A medical device is coated with a solution of TDMAC heparin and then allowed to air dry. Thereafter, the coated medical device is exposed to gamma ray radiation. The gamma radiation strengthens the bond of the TDMAC to the material of the medical device. In a variation of this method, TDMAC heparin coated and gamma ray irradiated medical device is heated for an extended period of time. This heating has been found to further strengthen the bond of the TDMAC heparin to the medical device.
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Chawla and Chang, Biomaterials, Medical Devices and Artificial Organs, "Nonthrombogenic Surface of Heparin", dated 1974, pp. 157-169, (no month available).
Chawla and Hayward, Pharmacology, "Effect of Gamma Radiation on Heparin", dated 1980, pp. 224-228, (no month available).
Crouther Ron
Flynn Daniel P.
Lagwinska Elizabeth
Bai Ari M.
Dudash Diana
Kinghorn Curtis D.
Sherwood Medical Company
Smith Montgomery W.
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