Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-03-20
2009-06-23
Horlick, Kenneth R. (Department: 1637)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
07550564
ABSTRACT:
A method of protecting the 3′ end of a DNA molecule from nuclease damage is disclosed. In one embodiment, the method comprises the step of exposing the DNA molecule to a preparation of DdrA protein.
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Bernstein D, et al., “Crystal structure of the Deinococcus radiodurans single-stranded DNA-binding protein suggests a mechanism for coping with DNA damage,” Proc. Natl. Acad. Sci. USA 101:8575-8580 (2004).
Clark A, “rec genes and homologous recombination proteins inEscherichia coli,” Biochimie. 73:523-532 (1991).
Harris D, et al., “Preserving genome integrity: the DdrA protein of Deinococcus radiodurans R1,” PLoS Biol. 2:e304 (2004).
Tanaka M, et al., “Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance,” Genetics 168:21-33 (2004).
Battista John R.
Cox Michael M.
Eggington Julie M.
Harris Dennis R.
Jolivet Edmond
Babic Christopher M.
Board of Supervisors of Louisiana State University and Agricultu
Horlick Kenneth R.
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
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