Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1991-08-13
1993-03-09
Stone, Jacqueline
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 691, 43525231, 43525235, 43525233, 4353201, 935 44, C12P 2106, C12N 120, C12N 1500
Patent
active
051926695
ABSTRACT:
The present invention is composed of novel recombinant DNA expression vectors which contain a transcriptional activating sequence, a translational activating sequence and a DNA sequence coding for a functional polypeptide, especially bovine growth hormone. The aforementioned translational activating sequences contain a ribosome binding site and are designed to provide high level expression of DNA that codes for virtually any functional polypeptide. The invention further provides transformed microbial host cells capable of producing bovine growth hormone and other functional polypeptides at high levels.
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Schoner Brigitte E.
Schoner Ronald G.
Crouch Deborah
Eli Lilly and Company
Parrish John E.
Stone Jacqueline
Whitaker Leroy
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