Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Avian cell – per se
Patent
1996-07-03
1997-11-25
Chan, Christina Y.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Avian cell, per se
435384, 530351, C12N 506, C12N 502, C07K 1452
Patent
active
056912005
ABSTRACT:
Immortal avian T lymphocyte cell lines which produce and secrete immune lymphokines are disclosed. These cell lines may be produced from T cells recovered from fowl which have been hyperimmunized in vivo. The activated T cells are first exposed in vitro to a mitogen effective for secondary stimulation thereof, and then virally transformed to produce an immortal cell line. When cultured in vitro, the cell lines produce and secrete immune lymphokines which may be administered to fowl to increase their resistance to infections.
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Kogut, M.H., McGruder, E.D., Hargis, B.M., Corrier, D.E., DeLoach, J.R. "In Vivo Activation of Heterophil Function in Chickens Following Injection with Salmonella Enteritidis-Immune Lymphokines," Journal of Leukocyte Biology, Jan. 1995, vol. 57, pp. 56-62.
DeLoach John R.
Hargis Billy M.
Kogut Michael H.
Moyes Rita B.
Stanker Larry H.
Chan Christina Y.
Deck Randall E.
Fado John D.
Silverstein M. Howard
The Texas A&M University System
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