Method to produce a tampon that inhibits exoprotein...

Details Method to produce a tampon that inhibits exoprotein... Method to produce a tampon that inhibits exoprotein...

2006-06-06

2006-06-06

Gitomer, Ralph (Department: 1655)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S054000

Reexamination Certificate

active

07056891

ABSTRACT:
A method to inhibit the production of exoproteins from Gram positive bacteria, such as harmful proteins produced byStaphylococcusspecies, is described. The method is particularly useful to inhibit the production of TSST-1, alpha-toxin and/or enterotoxins A, B and C fromStaphylococcus aureusbacteria. The method is based on exposing Gram positive bacteria to alkyl polyglycoside incorporated into an absorbent product. Alternate methods include bringing Gram positive bacteria into contact with the alkyl polyglycoside in other forms, e.g., when formulated with a pharmaceutically acceptable carrier or incorporated in or on a non-absorbent substrate. Typically, the alkyl polyglycoside has a hydrophilic/lipophilic balance (HLB) of at least about 10 and an alkyl group with an average of 8 to 14 carbon atoms.

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