Method to prevent vision loss

Details Method to prevent vision loss Method to prevent vision loss

2006-06-13

2006-06-13

Fay, Zohreh (Department: 1618)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S912000

Reexamination Certificate

active

07060695

ABSTRACT:
An improved method to treat conditions of the eye characterized by ocular neovascularization is provided in which patients are given and initial photodynamic therapy (PDT) treatment to destroy the neovasculature, and then are re-evaluated at least twice during the following 6 months, and retreated as necessary. Preferably, three retreatments are provided.

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patent: 5798349 (1998-08-01), Levy et al.
patent: WO 02/062384 (2002-08-01), None
patent: WO 02/062386 (2002-08-01), None
Michels, S. et al., “Changes in Neovascular Membranes and Normal Choroid Blood Vessels After Multiple Photodynamic Therapy Treatments!” Ophthalmologe 99(2):96-100 (2002).
Schmidt-Erfurth, U. et al., “Photodynamic Therapy with Verteporfin for Choroidal Neovascularization Caused by Age-Related Macular Degeneration: Results of Retreatmentsin a Phase 1 and 2 Study” Archives of Opthalmology 117(9):1177-1187 (1999).
Sickenberg, M. et al., “A Preliminary Study of Photodynamic Therapy Using Verteporfin for Choroidal Neovascularization in Pathologic Myopia Ocular Histoplasmosis Syndrome, Angioid Streaks, and Idiopathic Causes” Archives of Opthalmology 118(3):327-336 (2000).
Scott, L. et al., “Verteporfin.” Drugs & Aging 16(2):139-148 (2000).
Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group. “Photodynamic Therapy of Subfoveal Choroidal Neovascularization in Age-Related Macular Degeneration with Verteporfin” Arch. Opthalmol. 117: 1329-1345 (1999).

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