Method to prevent transplant rejection

Details Method to prevent transplant rejection Method to prevent transplant rejection

1996-12-02

1999-03-16

Coggins, Wynn Wood

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

604 49, 424810, 128898, A61N 130, I61M 3100

Patent

active

058823280

ABSTRACT:
Donor tissue containing antigen-presenting cells (APCs) can be modified to reduce rejection when the donor tissue is used as an allograft by exposing the donor tissue which has been treated with a photosensitizing agent having an absorption maximum between 400-900 nm to a wavelength absorbed by the photosensitizing agent so as to attenuate the APCs in the donor tissue but wherein the light is not cytotoxic to the APCs.

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