Method to measure the molecular diffusion and/or perfusion param

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A61B 505

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048097012

ABSTRACT:
By synchronizing the radio-frequency excitations of a nuclear magnetic resonance experiment with the heart beat of a patient, notable improvement is obtained in the measurement of the molecular diffusion parameters of the tissues studied. In particular, good images of the brain are obtained in this way: the parameter represented is the molecular diffusion constant.

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patent: 4712560 (1987-12-01), Schaefer et al.
Singer, "Nuclear Magnetic Resonance Blood Flow Measurements in the Human Brain", Science vol. 221, Aug. 1983, pp. 654-656.
Mansfield et al., "NMR Imaging in Biomedicine" 1982 pp. 30, 31.
Physics in Medicine & Biology, vol. 30, No. 4, Apr. 1985, pp. 345-349, The Institute of Physics, Bristol, GB; D. G. Taylor et al.: "The Spatial Mapping of Translational Diffusion Coefficients by the NMR Imaging Technique" *Page 345: Introduction; page 349, Lines 6-7*.
Comptes Rednus. Serie C. Sciences Chimiques, vol. 301, No. 15, Nov. 1985, pp. 1109-1112, Academie des Sciences, Paris, FR; D. Le Bihan et al.: "Resonance Magnetique.-Imagerie de Diffusion in Vivo Par Resonance Magnetique Nucleaire" pp. 1111-1112.

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