Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Gas produced in situ by chemical reaction
Patent
1985-07-30
1987-03-17
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Gas produced in situ by chemical reaction
424466, 424156, A61K 946, A61K 962, A61K 3310
Patent
active
046506691
ABSTRACT:
Described is a directly compressible formulation comprising calcium carbonate, citric acid, and a compression vehicle. In the preferred embodiment, the compression vehicle comprises a maltodextrin and lactose. The formulation can be compressed into an effervescent tablet system, which when placed in water effervesces in a relatively rapid dissolution releasing CO.sub.2 and resulting in a solution of monocalcium citrate.
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Alexander Thomas A.
Peterson Donald L.
Jeffers Jerome L.
Miles Laboratories Inc.
Rose Shep K.
Skord Jennifer L.
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