Method to isolate macromolecules using magnetically attractable

Details Method to isolate macromolecules using magnetically attractable Method to isolate macromolecules using magnetically attractable

1994-06-02

1996-06-04

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Treating animal or plant material or micro-organism

435262, 435267, C12S 320, C12S 300, C12N 108

Patent

active

055232310

ABSTRACT:
A method of recovering a biopolymer from solution involves the use of magnetically attractable beads which do not specifically bind the polymer. The beads are suspended in the solution. Then the polymer is precipitated out of solution and becomes non-specifically associated with the beads. When the beads are magnetically drawn down, the polymer is drawn down with them. The polymer can subsequently be resolubilized and separated from the beads.

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Chemical Abstracts, 112, 606 (1990), S. Flygare et al.: "Magnetic Aqueous Two-phase Separation in preparative Applications", abstract 96880s.
Chemical Abstracts, 82, 278, (1975), G. Bitton et al.: "Removal of Escherichia coli bacteriophage T7 by Magnetic Filtration", abstract 115953y.
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Munro et al., "Biotechnology Letters", 3(6) 297-302 (1981).

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