Method to inhibit adhesion of disease-causing microorganisms to

Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof

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514 12, 514 21, A61K 3718

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active

050135422

ABSTRACT:
A composition and method for the inhibiting of adhesion of disease-causing microorganisms, such as Streptococcus mutans, to tooth surrfaces, which composition contains as an active ingredient a non-immunogenic amino acid segment of a proline rich protein and which method comprises treating a calcium-containing mineral surface, such as a tooth surface, with the composition.

REFERENCES:
patent: Re31181 (1983-03-01), Kleinberg
patent: 4225579 (1980-09-01), Kleinberg
patent: 4314991 (1982-02-01), Sipos
patent: 4612190 (1986-09-01), Sato et al.
Gibbons et al., Inf. & Immun., Feb. 1988, pp. 439-445.
Schlesinger and Hay, "International Journal Peptide Protein Research", 17, 1981, 34-41.

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