Method to increase the yield and improve purification of...

Details Method to increase the yield and improve purification of... Method to increase the yield and improve purification of...

2009-08-06

2011-12-13

Lilling, Herbert J. (Department: 1657)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S107000, C435S108000, C435S109000, C435S110000, C435S111000, C435S112000, C435S113000, C435S114000, C435S115000, C435S116000, C435S128000, C435S136000, C435S143000

Reexamination Certificate

active

08076106

ABSTRACT:
A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to produce a keto acid by-product and an amino acid or amine product. Further reacting the keto acid by-product with a peroxide to increase the yield of additional amino acid or amine product.

REFERENCES:
patent: 4518692 (1985-05-01), Rozzell
patent: 4600692 (1986-07-01), Wood et al.
patent: 4826766 (1989-05-01), Rozzell
patent: 5316943 (1994-05-01), Kidman et al.
patent: 5688672 (1997-11-01), Kretzschmar et al.
patent: 6197558 (2001-03-01), Fotheringham
patent: 6365380 (2002-04-01), Liu et al.
patent: 7588923 (2009-09-01), Fotheringham et al.
patent: 2003/0032149 (2003-02-01), Lalonde

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